This study was intended to determine the level of factors affecting the decision of 4th year BS Accountancy students from College of Maasin to work after graduation or to take the 2022 CPALE. In order to determine the factors affecting the decision of the graduating Accountancy students, the researchers adopted the descriptive survey design. Descriptive survey is a sort of descriptive study that uses surveys to collect data on a variety of issues. The goal of this information is to see (...) how different circumstances can be obtained among the respondents. The following results were derived in the course of the conduct of this study; There is bigger percentage of female than of male where 26 out of 27 belongs to the age group of 20 to 22. Majority of the student’s parent’s occupation status is working. Conversely, most of them only earns P2,000 to P5,000 per month even though the household member earning for a living is 1 to 4 members, the first 3 factors namely financial status, peer pressure and parent’s influence were found to slightly affect the decision of the student with regards to taking the CPALE or to work after graduation. The last factor, school’s teaching influence turned out that it somewhat affects the decision of the students, there is a significant difference between the teaching influence factor and the demographic profile of gender while on the age and parent’s occupation status, it has a significance difference with financial status factor. As BSA students taking a course where a licensure examination awaits after graduation, it is necessary to take some factors into consideration before coming up into a decision regarding taking the CPALE or to work after graduation. Based on the results of the study, the level of factors to affect the decision of the students was determined. It has been shown in the results that the three factors namely financial status, peer pressure and parent’s influence can slightly affect the student’s decision. However, among three, peer pressure has the highest weighted mean rating of 2.86. On the other hand, the school’s teaching influence has the lowest weighted mean rating of 2.29 which means it can somewhat affect the decision of the student. (shrink)

Dating and hookup apps (DHAs) are now widely used and may be transforming our intimate relationships. The apps are beneficial in fostering intimate connections among those who are lonely, who are members of minority or marginalized groups, or who live nomadic lifestyles because of work or recreational travel. However, the wider social and relational changes that DHAs portend are merely beginning to be seriously discussed by academics (Arias et al., 2017). In this chapter, we employ concepts from the philosophy of (...) technology that inform our analysis of these changes. We also collate some of the morally significant impacts of DHAs and present some of the elements of the architecture of DHAs that facilitate them. Although there are many reasons to be concerned about DHAs, we argue that there is room for cautious optimism that DHAs may be vehicles of positive social and moral change. (shrink)

We discuss recent progress in the development of cognitive ontologies and summarize three challenges in the coordinated development and application of these resources. Challenge 1 is to adopt a standardized definition for cognitive processes. We describe three possibilities and recommend one that is consistent with the standard view in cognitive and biomedical sciences. Challenge 2 is harmonization. Gaps and conflicts in representation must be resolved so that these resources can be combined for mark-up and interpretation of multi-modal data. Finally, Challenge (...) 3 is to test the utility of these resources for large-scale annotation of data, search and query, and knowledge discovery and integration. As term definitions are tested and revised, harmonization should enable coordinated updates across ontologies. However, the true test of these definitions will be in their community-wide adoption which will test whether they support valid inferences about psychological and neuroscientific data. (shrink)

A wide variety of ontologies relevant to the biological and medical domains are available through the OBO Foundry portal, and their number is growing rapidly. Integration of these ontologies, while requiring considerable effort, is extremely desirable. However, heterogeneities in format and style pose serious obstacles to such integration. In particular, inconsistencies in naming conventions can impair the readability and navigability of ontology class hierarchies, and hinder their alignment and integration. While other sources of diversity are tremendously complex and challenging, agreeing (...) a set of common naming conventions is an achievable goal, particularly if those conventions are based on lessons drawn from pooled practical experience and surveys of community opinion. We summarize a review of existing naming conventions and highlight certain disadvantages with respect to general applicability in the biological domain. We also present the results of a survey carried out to establish which naming conventions are currently employed by OBO Foundry ontologies and to determine what their special requirements regarding the naming of entities might be. Lastly, we propose an initial set of typographic, syntactic and semantic conventions for labelling classes in OBO Foundry ontologies. Adherence to common naming conventions is more than just a matter of aesthetics. Such conventions provide guidance to ontology creators, help developers avoid flaws and inaccuracies when editing, and especially when interlinking, ontologies. Common naming conventions will also assist consumers of ontologies to more readily understand what meanings were intended by the authors of ontologies used in annotating bodies of data. (shrink)

We discuss recent progress in the development of cognitive ontologies and summarize three challenges in the coordinated development and application of these resources. Challenge 1 is to adopt a standardized definition for cognitive processes. We describe three possibilities and recommend one that is consistent with the standard view in cognitive and biomedical sciences. Challenge 2 is harmonization. Gaps and conflicts in representation must be resolved so that these resources can be combined for mark-up and interpretation of multi-modal data. Finally, Challenge (...) 3 is to test the utility of these resources for large-scale annotation of data, search and query, and knowledge discovery and integration. As term definitions are tested and revised, harmonization should enable coordinated updates across ontologies. However, the true test of these definitions will be in their community-wide adoption which will test whether they support valid inferences about psychological and neuroscientific data. (shrink)

As part of a trend in modern cognitive science, cognitive linguist, George Lakoff, and philosopher, Mark Johnson claim to provide a biologically-based account of subsymbolic meaningful experiences. They argue that human beings understand objects by extrapolating from their sensory motor activities and primary perceptions. Lakoff and Johnson’s writings have generated a good deal of interest among scholars of Early China because they maintain that “our common embodiment allows for common stable truths.” Although there are many grounds on which Lakoff and (...) Johnson’s theories have been criticized, this essay focuses in particular on problems related to their schema of Self as Container. Lakoff and Johnson contend that there are no pure experiences outside of culture, while nevertheless arguing that the experience of being a closed-off container is “direct.” “The concepts OBJECT, SUBSTANCE and CONTAINER emerge directly,” they write. “We experience ourselves as entities, separate from the rest of the world—as containers with an inside and an outside.” By “emerge directly,” they do not mean emerging free of culture, but rather that some experiences within culture, specifically physical experiences, are more directly given than others. My study explores the pitfalls of presuming the “direct” experience of containment makes good sense of texts from Early China (ca. 500–100 B.C.E). (shrink)

Proza e shkurtër në këtë vëllim, e ribashkuar nën titullin „Me duar në xhepa të qepur”, tërheq konflikte midis ekzistencës dhe thelbit, duke projektuar ngërçe, aporie identitare dhe shëmbëlltyra komunikimi. 1-0 (?) është një satirë për futbollin dhe aranzhimet - në favor të skuadrave apo lojtarëve të caktuar - që u prodhuan intensivisht gjatë periudhës socialiste, të dominuara nga gënjeshtra, mistifikimi dhe faji. GIONÍ diskuton për komplekset adoleshente-adoleshente të disa krijesave me status të pasigurt, të përhumbur nga dështimi dhe dështimi, (...) të cilat autori, në frymën amerikane, i shpëton në fund, duke i dërguar në punë (pa na shpjeguar sesi do të ishte i mundur shpëtimi ontologjik). Mekanizmi epik në XHAMANTANI BOJËALLI duket i huazuar nga Mircea Eliade, i zbatuar vetëm në dimensione deterministe, ndër të cilat zbulimi I paautenticitetit të një martese është më pak problematik. Tek KU ISHA NË VEND, strategjitë e fiksionit autobiografik funksionojnë me mjeshtëri, autori rikujtues na çon nëpër labirintin e fatit drejt arratisjes në brendësi. Katër tekstet e fundit (në anglisht) janë drafte për më vonë. Një sërë ilustrimeve mbështesin tekstet dhe, në tensionin e ideve, gjarpërimet e rrëfimit të Florentin Smarandache befasojnë këndshëm, duke shkaktuar keqardhje që autori, shumë më i tërhequr nga shkenca, por edhe nga avangarda, nuk kërkonte një konservator fati letrar në prozë. Kam bindjen se do të jetë një sukses. (shrink)

_La Peste_, originally published in 1947 by the Nobel Prize-winning writer Albert Camus, chronicles the progression of deadly bubonic plague as it spreads through the quarantined Algerian city of Oran. While most discussions of fictional examples within aesthetics are either historical or hypothetical, Camus offers an example of "pestilence fiction." Camus chose fiction to convey facts--about plagues in the past, his own bout with tuberculosis at age seventeen, living under quarantine away from home for several years, and forced separation from (...) his wife who remained in Algiers while he was abroad in Nazi-occupied France. His own lived experiences undergird an imaginative account of shared human realities with which we can identify: vulnerability to the disease, isolation, fear, and finally humanitarianism. _The Plague_ teaches us to neither covet nor expect what we so casually took for granted. This collection of original essays on philosophical themes in _The Plague_ is of special relevance during and in the aftermath of Covid-19 but also provides reflections that will be of lasting value to those interested in this classic work of literature. The novel explores questions of enduring importance. Do we collectively meet the threshold of ethical behavior posed by Camus who wrote, "What's true of all the evils in the world is true of plague as well. It helps men to rise above themselves"? Or does the absurd undermine the compassionate? Do "heroes" dutifully fight a plague with "common decency," or does human nature resign itself to the normalization of uncontrollable suffering and death? There are myriad ways to approach the novel and this volume encourages readers to ponder human dilemmas in fictional Oran informed by our current pandemic. Series editor forward by Richard Eldridge. List of Contributors includes Steven G. Kellman, Jane E. Schultz, Andrew Edgar, Kathleen Higgins, Edward B. Weiser, Cynthia A. Freeland, and Margaret E. Gray; see "Introduction" by Peg Brand Weiser below. (shrink)

Epistemologists often claim that in addition to belief and disbelief there is a third, neutral, doxastic attitude. Various terms are used: ‘suspending judgment’, ‘withholding’, ‘agnosticism’. It is also common to claim that the factors relevant to the justification of these attitudes are epistemic in the narrow sense of being factors that bear on the strength or weakness of one’s epistemic position with respect to the target proposition. This paper addresses two challenges to such traditionalism about doxastic attitudes. The first concerns (...) the relevance of non-epistemic factors we might call "future-comparative" – e.g., that you’ll have more decisive evidence on whether p tomorrow – to the justification of suspending judgment. The second, from Jane Friedman, is to explain the point of the neutral attitude without appealing to inquiry and thus taking goal-related factors, which are not epistemic, such as the value of the goal or the prospects for finding means to achieve it, to bear on the justification of the neutral attitude. My defense of traditionalism relies on distinguishing three ways of being neutral on a question: agnosticism, inquiry and suspension of judgment. Traditionalism is saved because, of these, agnosticism alone is a genuine doxastic attitude. (shrink)

O renascimento do pragmatismo foi acompanhado por uma série de filósofas feministas que se esforçaram para resgatar do esquecimento as pensadoras que fizeram parte do movimento pragmatista clássico do final do século XIX e primeira metade do século XX. O presente trabalho visa introduzir aos leitores de língua portuguesa esse trabalho a partir de uma breve exposição das pensadoras Jane Addams, Mary Parker Follet, Charlotte Perkins Gilman, Mary Whiton Calkins e Ella Flagg Young.

Readers assume that commonplace properties of the real world also hold in realistic fiction. They believe, for example, that the usual physical laws continue to apply. But controversy exists in theories of fiction about whether real individuals exist in the story’s world. Does Queen Victoria exist in the world of Jane Eyre, even though Victoria is not mentioned in it? The experiments we report here find that when participants are prompted to consider the world of a fictional individual (“Consider (...) the world of Jane Eyre…”), they are willing to say that a real individual (e.g., Queen Victoria) can exist in the same world. But when participants are prompted to consider the world of a real individual, they are less willing to say that a fictional individual can exist in that world. The asymmetry occurs when we ask participants both if a real person is in the character’s world and if the person would appear there. However, the effect is subject to spatial and temporal constraints. When the person and the character share spatial and temporal settings, interchange is more likely to occur. These results shed light on the author’s implicit contract with the reader, which can license the reader to augment a fictional world with features that the author only implicates as part of the work’s background. (shrink)

In philosophical aesthetics, discussions on design objects place the notion of Functional Beauty at the fore. Such a philosophical approach can be found in Jane Forsey’s book The Aesthetics of Design that focuses on the notion of function to promote the aesthetic value of design and develops an interpretation of Kantian Dependent Beauty around it. Lucía Jiménez Sánchez has recently put forward several flaws of Functional Beauty accounts. She presented several practical cases as evidence for the narrowness of Functional (...) Beauty accounts. Two cases are presented against Jane Forsey’s theory of Dependent Beauty, holding that it excludes other properties from appreciation that are not necessarily related to functionality, i.e., expres- sive properties. The purpose of this article is to show that these criticisms leveled at Jane Forsey’s proposal for an aesthetic theory of design are unfounded and are based on a misun- derstanding of the structure of judgments of beauty in her system. Despite this, these criticisms highlight the need to clarify the purpose of the aesthetics of design. (shrink)

Wir wissen, dass eine Transformation von globalem Ausmaß bereits begonnen hat, und wir wissen, dass ihre Entfaltung nicht vorhersehbar ist. Wir können sicher sein, dass es eine Herausforderung sein wird: Wir werden inmitten tiefgreifender Veränderungen leben, unser Überleben wird ständig auf dem Spiel stehen. Werden wir das Verständnis, die Weisheit erreichen, um diese Herausforderung zu bestehen? Hier sind einige Gedanken und Überlegungen, die uns helfen, den Zustand zu erreichen, in dem wir eine positive Antwort geben können. -/- Zurückblicken, um nach (...) vorne zu sehen -/- Dies wird nicht das erste Mal in der Geschichte sein, dass für die Menschheit eine Periode der Transformation auf globaler Ebene angebrochen ist. Der Wissenschaftsphilosoph Holmes Rolston wies darauf hin, dass unsere „große Geschichte“ drei solcher Transformationen umfasst – wahre „Urknalle“.1 Die erste war der physische Urknall, der vermutlich vor etwa 13,8 Milliarden Jahren stattfand. Es gebar das manifeste Universum mit seinen Quantenteilchen, vielfältigen Arten von Energien und Milliarden von Galaxien. Es führte zur Bildung von Sonnensystemen mit Sonnen und Planeten und Energieflüssen, die die Entwicklung von lebenden (glücklich gelegenen) Planeten ermöglichen, die aktive Sonnen umkreisen. Eine weitere grundlegende Transformation – ein „zweiter Urknall“ – war die Entstehung lebender Organismen in den komplexen Systemen, die sich auf der Erde und vermutlich auch auf anderen Planeten entwickelt haben. Es wird angenommen, dass diese Transformation vor etwa 3,8 Milliarden Jahren stattgefunden hat. Es begann mit der Entstehung einzelliger Prokaryoten in der Ursuppe, die die Oberfläche des Planeten bedeckte. Der „dritte Urknall“ soll vor etwa 120.000 Jahren stattgefunden haben. Es hat das Bewusstsein unserer Spezies grundlegend verändert – „entwickelt“. Homo soll sapiens geworden sein. Zu den evolutionären Vorteilen des weiterentwickelten Bewusstseins gehörte eine flexiblere und schnellere Form der Kommunikation. Die Kommunikation war nicht mehr auf halbautomatische Reaktionen beschränkt, die durch wiederkehrende Bedingungen und Ereignisse ausgelöst wurden; Anstatt sich auf Zeichen zu beschränken, basierte die menschliche Kommunikation auf einvernehmlich entwickelten Symbolen. -/- Die Entwicklung der Symbolsprache war ein großer Sprung. Einerseits brachte es soziale Strukturen hervor, die auf kollektiv erworbener Bedeutung beruhten, und andererseits produzierte es verbesserte manipulative Fähigkeiten. Gesellschaften könnten sich auf der Grundlage gemeinsamer Kulturen entwickeln, die mächtige Technologien einsetzen. Homo sapiens begann andere Arten zu dominieren und wurde zu einem Schlüsselfaktor in der Evolution des Lebens in der Biosphäre. Der dritte Urknall erzeugte eine Explosion der menschlichen Bevölkerung, aber er brachte nicht die Weisheit hervor, die sicherstellen würde, dass die erweiterte Bevölkerung das Gleichgewicht aufrechterhalten könnte, das für das Gedeihen des Lebens auf diesem Planeten unerlässlich ist. Diese Gleichgewichte wurden immer mehr beeinträchtigt. Der kurzsichtige Einsatz von Technologie und die Missachtung natürlicher Kontrollmechanismen brachten die Menschheit dorthin, wo sie heute ist: an einen „Chaos-Punkt“, an dem die Wahl klar ist: zwischen Zusammenbruch und Durchbruch.2 Eine weitere globale Transformation ist unvermeidlich geworden und ist es noch tatsächlich im Gange: ein vierter Urknall. Es ist an der Zeit, die Lehren aus der Geschichte zu ziehen. Der Aufbau unserer Herrschaft auf dem Planeten hängt davon ab, ob wir die Herausforderung dieser Transformation meistern. -/- Die erste und grundlegende Lektion ist einfach und offensichtlich. Wir haben uns von der natürlichen Welt getrennt und müssen zurückkommen – nicht um Wilde und „Primitive“ zu werden, sondern Wesen, die auf die Welt um sie herum eingestimmt sind, die im Einklang mit den Rhythmen und Gleichgewichten der Natur leben und kompatibel erschaffen und nachhaltige eigene Rhythmen und Balancen. Wir sind nicht mehr auf die Rhythmen und Balancen der Natur ausgerichtet. Obwohl wir durch unsere biologische Evolution in diese Rhythmen und Balancen „eingebaut“ sind, haben wir unsere eigenen künstlichen Rhythmen und gefährlichen Balancen geschaffen, die die natürlichen Rhythmen ignorieren und oft mit ihnen in Konflikt stehen. Mit der Sonne aufzugehen und sich mit der Sonne zurückzuziehen bedeutet, sich an den zirkadianen 24-Stunden-Rhythmus anzupassen, der durch die Bewegung der Erde um die Sonne geschaffen wurde, und die sogenannten primitiven Menschen leben immer noch in Harmonie damit, und das tun die meisten auch die restlichen indigenen und traditionellen Kulturen. Aber moderne Menschen missachten die Rhythmen und Gleichgewichte der Natur und glauben, dass sie sie ersetzen können, indem sie Lichter und andere künstliche Annehmlichkeiten mit dem Umlegen eines Schalters ein- und ausschalten. Doch der menschliche Körper passt sich nicht den künstlichen Rhythmen an, und wir leiden unter den Folgen. -/- 3Die Wirksamkeit des Immunsystems ist beeinträchtigt, und trotz einer Flut von biochemischen Medikamenten breiten sich Krankheiten aus. Moderne Bevölkerungen sind Stadtbewohner und haben nur begrenzten Kontakt mit der Natur. Sie leben in einer künstlichen Welt und denken, dass es die reale Welt ist. Sie halten sich anderen Lebensformen überlegen und glauben, die Natur nach Belieben beherrschen zu können. Noch vor fünfzig Jahren musste die Tierintelligenzforscherin Jane Goodall gegen die damals noch vorherrschende Überzeugung ankämpfen, dass ChiMenschen sind biochemische Reiz-Reaktions-Mechanismen, keine lebenden und fühlenden Wesen. Heute erkennen wir, dass nicht nur höhere Säugetiere, alle lebenden Organismen und sogar Bäume und Pflanzen sensible Lebewesen sind und sich in dieser Hinsicht nicht grundlegend von uns unterscheiden. Es liegt im besten Interesse unseres körperlichen und geistigen Wohlbefindens, dass wir diese Missverständnisse und fehlerhaften Verhaltensweisen korrigieren. Wenn wir dies tun, gewinnen wir unsere natürliche Gesundheit und Vitalität zurück. Die heilende Wirkung natürlicher Substanzen und Lebensweisen war schon in der Antike Heilern und Weisen bekannt. Seit Hippokrates, der als Vater der modernen Medizin gilt, suchen Mediziner nach Substanzen und Methoden, die das Gleichgewicht und die Verbindung zwischen Mensch und Natur wiederherstellen. Heute wird dieser Anspruch überschattet von einer oft kommerziell motivierten Abhängigkeit von synthetischen Substanzen und naturverachtenden Praktiken. Die Szene ist nicht nur negativ: Wie wir sehen werden, gibt es positive Entwicklungen in allen Bereichen des menschlichen Strebens, einschließlich Heilung und Medizin. Die Verbindung mit der Natur ist ein Hauptziel der alternativen Heilmethoden, die als Informations- und Energiemedizin bekannt sind. Diese Form der Heilung erlebt in verschiedenen Teilen der Welt, vor allem im Orient, eine Renaissance. Shirin yoku, die japanische Kunst des Waldbadens, ist ein Paradebeispiel. Um es zu praktizieren, müssen wir in einen Wald gehen und uns auf seine Rhythmen und Energien eingestimmt fühlen – den Wind durch die Blätter rauschen hören, das Lichtspiel auf der Oberfläche eines Teichs spüren, mit den Wolken schweben, wenn sie sich durch den Himmel bewegen. Psychotherapeuten finden, dass sogar die Geräusche der Natur, das Zwitschern der Vögel, das Rauschen der Bäche heilend wirken. Einfach in einem Wald zu sein oder neben einem Baum zu stehen, beruhigt und heilt das Nervensystem. Eine weitere wesentliche Aufgabe ist es, positive Entwicklungen in der Gesellschaft zu erkennen und daran anzuknüpfen. -/- Es gibt positive Entwicklungen in der Gesellschaft, und es gibt gesunde, lebensspendende und erhaltende Prozesse in der Natur. Wir könnten wieder in die Natur eintauchen und an positiven Entwicklungen in der Gesellschaft teilhaben. Und doch gelingt uns das nicht. Wir beschreiten einen Weg, der eher zum Zusammenbruch als zum Durchbruch führt. Wir müssen überdenken, wie wir gehen, und vor allem, wohin wir gehen. Wir sind eine von mehr als hundert Millionen Arten in der Biosphäre, wobei jede Art Millionen und in einigen Fällen Milliarden von Individuen umfasst. Unter all diesen Arten und Individuen befinden wir uns in einer privilegierten Position: Wir haben ein hoch entwickeltes Gehirn und Bewusstsein. Dies ermöglicht uns zu fragen, wer wir sind, was die Welt ist und wie wir in der Welt leben können und sollen. Ein fortgeschrittenes Bewusstsein ist eine einzigartige Ressource, und wir machen keinen guten Gebrauch davon. Wir stellen nicht die richtigen Fragen und suchen nicht nach den richtigen Antworten, sondern gehen einfach vorwärts und vertrauen auf das Glück. Wir haben unsere Zahl erhöht, aber nicht die Vorteile, die unser Bewusstsein denen verleihen könnte, die wir in die Welt bringen. Wir haben ausgeklügelte Technologien entwickelt und angewendet, um unseren Bedürfnissen und Wünschen gerecht zu werden, haben aber die Mehrheit der fortgeschrittenen Arten beschädigt oder zum Aussterben gebracht. Fünfzig Prozent aller Wildtiere auf dem Planeten sind verschwunden, und jeden Tag verschwinden vierundvierzigtausend Populationen lebender Arten. Wir sind zu einer Gefahr für das Leben in der Biosphäre geworden. Die Geschichte lehrt uns, dass Urknalle, globale Transformationen, nicht unbedingt eine gerechte und blühende Welt hervorbringen; sie können zu einem Zusammenbruch führen. Wir haben die Schwelle eines vierten Urknalls erreicht, und wir tun nicht, was wir können, um einen Zusammenbruch abzuwenden. Der Großteil der heutigen Bevölkerung ist frustriert und depressiv und wird gewalttätig. Menschen leiden unter einer veränderten -/- über Klima, Umweltverschmutzung und unzählige Formen der Umweltzerstörung. Millionen durchstreifen den Planeten auf der Suche nach einem Ort, an dem sie nur überleben können. Die Lehren der Geschichte liegen vor uns, und wir ignorieren sie. Dennoch könnten wir die Lektionen lernen und unsere Wege korrigieren. Wir sind durchaus in der Lage, auf diesem Planeten zu leben, ohne das Gleichgewicht und die Ressourcen zu zerstören, die für ein gesundes Leben für uns und andere Arten erforderlich sind. Keine Spezies müsste dezimiert, unterworfen oder zum Aussterben getrieben werden, um uns am Leben zu erhalten. Wir könnten nachhaltig leben, mit anderen Arten koexistieren und die Grenzen des Lebens auf dem Planeten respektieren. Wir könnten die Verfügbarkeit lebenswichtiger Ressourcen für alle Menschen und Bevölkerungsgruppen sicherstellen. Dennoch treiben wir unzählige Arten zum Aussterben und schädigen die gemeinsame Umwelt. Die bloße Tatsache, dass wir es geschafft haben, als biologische Spezies fünf Millionen Jahre und als bewusste Spezies fünfzigtausend Jahre zu überleben, ist ein Beweis dafür, dass unsere grundlegende Natur nicht das Problem ist. Es ist nicht die Masse der menschlichen Bevölkerung, die dafür verantwortlich ist, zu einer Geißel des Lebens auf dem Planeten zu werden, sondern nur ein Teil. Die Frage ist, warum dieses Segment unhaltbare und jetzt kritische Bedingungen für geschaffen hat die höheren Formen des Lebens auf der Erde? Und kann es sich rechtzeitig ändern und transformieren, um eine große Katastrophe zu vermeiden? Theologische und mystische Annahmen wurden manchmal als Grund dafür angeführt, dass wir zu dem wurden, was wir sind, aber unser Verhalten göttlichen oder anderen transzendenten Ursachen zuzuschreiben, ist nicht die Antwort. Wir sind weder Engel noch Teufel. Wir wurden zur Geißel, zu der wir unbeabsichtigt geworden sind. Zu Beginn des Neolithikums begann ein Teil der Menschheit, die Ressourcen des Planeten ohne Rücksicht auf irgendetwas und irgendjemanden zu nutzen und sich nur darauf zu konzentrieren, seinen eigenen Komfort und seine eigene Macht zu verbessern. Auf einem endlichen und voneinander abhängigen Planeten führte dies zu unausgewogenen und unhaltbaren Bedingungen. Der egozentrische Umgang mit Ressourcen hat das Netz des Lebens beschädigt. Die menschliche Spezies wurde zu einer Bedrohung für alles Leben auf dem Planeten und auch für sich selbst: Die Gesundheit des Netzes des Lebens ist eine Vorbedingung für die Gesundheit der dort lebenden Spezies. Dies ist eine relativ junge Erkenntnis. Jahrtausendelang gingen die Menschen ihren Daseinsaufgaben nach, ohne sich bewusst zu sein, dass die unreflektierte Verfolgung ihrer eigenen Interessen um sie herum zum Fluch des Lebens wird. -/- Wir sind zu einem Fluch für das Leben auf diesem Planeten geworden; Wir haben die Welt zu einem Spielzeugladen gemacht, in dem wir die leistungsstarken Spielzeuge bauen, die unseren wahrgenommenen Interessen dienen. Wir spielen mit unseren Spielsachen unabhängig davon, ob sie wirklich unseren Bedürfnissen dienen, und ohne Rücksicht auf die Bedürfnisse anderer. Wir setzen die Energie des Atoms frei und nutzen sie, um Systeme anzutreiben, die unsere Bedürfnisse befriedigen. Wir leiten Elektronenströme in integrierte Schaltkreise und verwenden die Schaltkreise, um die Technologien zu beherrschen, die unseren Anforderungen an Kommunikation und Information dienen. Wir spielen im globalen Spielzeugladen ohne Rücksicht auf die Folgen für andere und für den gesamten Laden. Dies ist ein kurzsichtiges und gefährliches Verhalten. Wir greifen auf Energie auf eine Weise zu, die nicht unseren wirklichen Bedürfnissen dient, sondern nur unseren kurzfristigen, egozentrischen Bedürfnissen. Ähnlich kurzsichtig manipulieren wir Informationen. Beispiele dafür sind die Atombombe und das Atomkraftwerk auf der einen Seite und der Computer mit seinem Netzwerk aus globalem Geschwätz auf der anderen Seite. Atomkraft, selbst für friedliche Zwecke, und künstliche Intelligenz, selbst wenn sie gut gemeint ist, sind gefährliche Spielzeuge. Sie können zu technologischen Überschreitungen werden, die am Ende unser Leben und das gesamte Lebensnetz in der Biosphäre schädigen. Wir sind an sich gut, aber egozentrisch und kurzsichtig. Aber das kann nicht unwidersprochen bleiben. Die Zeit, in der wir naiv mit mächtigen Spielzeugen spielen konnten, ist vorbei. Ihre unvorhergesehenen „Nebenwirkungen“ sind zu einer Bedrohung für alles Leben auf dem Planeten geworden, einschließlich unseres eigenen. -/- Vorwärts gehen. -/- Wir sind an der Schwelle des vierten Urknalls angekommen. Was machen wir jetzt? Wenn wir gedeihen oder auch nur überleben wollen, muss sich unser Bewusstsein ändern. Gelingt dies nicht, wird der nächste Urknall unser letzter sein. Eine globale Transformation ist ein riskanter Prozess: Soll sie nicht zum Zusammenbruch, sondern zum Durchbruch führen, muss sie gesteuert werden. Wir können mit der bewussten Führung unserer Evolution beginnen, indem wir Gandhis Rat folgen: Sag anderen nicht, was sie tun sollen; Werde du selbst zu dem, was sie und die Welt werden sollen. Unsere wesentliche Aufgabe ist es, die Transformation der Welt zu werden. Wir müssen Ausdruck eines reifen und gesunden Lebens in der Biosphäre sein. Wenn diese kritische Masse erreicht wird, wird der „vierte Urknall“ nicht das Ende des Lebens auf dem Planeten markieren. Es wird eine disruptive globale Transformation sein, aber keine destruktive. Es wird eine neue Phase in der Amtszeit der Menschheit auf dem Planeten auslösen und nicht das Ende dieser Amtszeit. Es ist an der Zeit, die Lehren aus der Geschichte zu ziehen – zurückzublicken, um nach vorne zu sehen. Das Überleben einer fortgeschrittenen Spezies und die Zukunft des Lebensnetzes auf diesem Planeten liegt in unseren Händen. Noch nie waren so viele von der Weisheit so weniger abhängig. Wir müssen erwachen – um erwachsen zu werden. Die Kraft des Bewusstseins zu nutzen, die in unseren Händen liegt. Es ist nicht an der Zeit zu fragen, ob wir den vierten Urknall, die bereits begonnene globale Transformation, überstehen werden. Es ist an der Zeit, sich daran zu machen, es zu schaffen. (shrink)

A discussion of L.A. Paul's 'Transformative Experience' from an Author Meets Critics session at the 2015 Pacific APA.

Recent work in the philosophy of biology argues that we must rethink the biological individual beyond the boundary of the species, given that a key part of our essential functioning is carried out by the bacteria in our intestines in a way that challenges any strictly genetic account of what is involved for the biological human. The gut is a kind of ambiguous other within our understanding of ourselves, particularly when we also consider the status of gastro-intestinal disorders. Hegel offers (...) us theoretical tools to describe and understand our relationship to our gut. His description of our selves as continually mediated through otherness is strikingly compatible with the kind of structure contemporary biology presents us with. His accounts of digestion and habit, contextualized by his logic, help point toward an understanding of selfhood as porous and yet still capable of being sufficiently unified for us to make sense of ourselves, one which allows us to acknowledge otherness within us while still having enough unity for agency. (shrink)

Two major lines of argument support the notion that Hildegard of Bingen’s metaphysics is peculiarly gynocentric. Contra the standard commentary on her work, the focus is not on the notion of viriditas; rather, the first line of argument presents a specific delineation of her ontology, demonstrating that it is a graded hierarchy of beings, many of which present feminine aspects of the divine, and all of which establish the metaphysical notion of interpenetrability. The second line of argument specifically contrasts her (...) thought to that of Aquinas and Meister Eckhart, noting areas of similarity and difference. It is concluded that the visionary origins of Hildegard’s work may have to some extent precluded our understanding of it, and that her work merits consideration not only philosophically and theologically but from the standpoint of its early presentation of a gynocentric worldview. (shrink)

When discussing the problem of evil, philosophers often distinguish between physical evil (harm caused within the natural world such as natural disasters, disease, and the like), and moral evil (harm caused by human agency). Mapping this traditional distinction is mapped onto the third section of Fichte’s The Vocation of Man would at first seem fairly straightforward: for Fichte, evil arising from nature occurs through “blind mechanism” and is unfree; in contrast, evil done by human beings arises out of free agency. (...) The answer may be more complicated, however, in two different ways. First, Fichte holds that nature is to be cultivated and controlled by human beings so that it is no longer a source of harm; this may imply that the continuing harm done by nature is the result of humans’ failure to have sufficiently tamed nature. In that case, some of the harm caused by nature may be attributable to free human causality and thus no longer be a clearcut instance of natural evil. Second, Fichte repeatedly states that those who fail to act morally and who fail to conform their wills to the moral law are still be in the power of the mechanisms of nature. Even though we must think of them as free, Fichte compares their actions to the operation of nature and its mechanism of necessity. By presenting a careful and nuanced Fichtean account of the traditional distinction between physical and moral evil, we can better appreciate how Fichte understood the meaning and scope of human responsibility. (shrink)

Three professors reflect on the experience of creating a learning community of 22 students by linking courses in Literature and Ethics. The project demonstrates practical strategies for incorporating feminist scholarship and pedagogy into the core curriculum and for integrating core courses from diverse disciplines.

Translation of "Von der Armut am Geiste; ein Dialog des jungen Lukács," by Ágnes Heller. This translation originally appeared in The Philosophical Forum, Spring-Summer 1972.

In the remainder of this article, we will disarm an important motivation for epistemic contextualism and interest-relative invariantism. We will accomplish this by presenting a stringent test of whether there is a stakes effect on ordinary knowledge ascription. Having shown that, even on a stringent way of testing, stakes fail to impact ordinary knowledge ascription, we will conclude that we should take another look at classical invariantism. Here is how we will proceed. Section 1 lays out some limitations of previous (...) research on stakes. Section 2 presents our study and concludes that there is little evidence for a substantial stakes effect. Section 3 responds to objections. The conclusion clears the way for classical invariantism. (shrink)

Michelle’s thesis explores the extent to which a researcher could contribute to change by engaging leaders in conversations that might intensify commitment to or the direction of their actions around socio-environmental decline in Bermuda as a country historically organised in the tradition of an entrepreneurial for-profit enterprise. The framing of a space to reflect on highlighted the significance of time that led to the bricolage design of a heuristic device called a moon gate. Time, the keystone of the moon gate, (...) created a prism lighting up the twists and turns of kaleidoscopic images of the chaos of the markets and the creative diversity of human and nonhuman participants. She undertook a philosophical approach with her study of the contested space of time around sensitivity to maintaining a fulcrum point based on the wellbeing of people and planet. (shrink)

O presente trabalho visa apresentar a solução dada por Santo Agostinho ao problema do mal, aliado à aparente contraditoriedade entre a presciência de Deus e a liberdade humana. Para isto, será útil como bibliografia principal do filósofo sua obra De libero arbitrio, um livro em forma de diálogo onde o pensador esclarece suas posições acerca do livre-arbítrio e da presciência divina.

This paper explores the role of generics in social cognition. First, we explore the nature and effects of the most common form of generics about social kinds. Second, we discuss the nature and effects of a less common but equally important form of generics about social kinds. Finally, we consider the implications of this discussion for how we ought to use language about the social world.

A minimal truthmaker for a given proposition is the smallest portion of reality which makes this proposition true. Minimal truthmakers are frequently mentioned in the literature, but there has been no systematic account of what they are or of their importance. In this article we shall clarify the notion of a minimal truthmaker and argue that there is reason to think that at least some propositions have minimal truthmakers. We shall then argue that the notion can play a useful role (...) in truthmaker theory, by helping to explain the truth of certain propositions as precisely as possible. (shrink)

ABSTRACT Temporal dynamists argue that we should believe that there exists temporal passage because there being passage is the best explanation for the presence of our temporal phenomenology. Presentists argue that presentism is the best version of temporal dynamism. Therefore, conditional on us accepting temporal dynamism, we should accept presentism. In this paper it is argued that if we understand temporal passage as the presentist does, such an argument can succeed only if dualism is true. Thus, we conclude, either presentists (...) should embrace dualism, or they should reject any argument for presentism that proceeds via any such argument for temporal passage that proceeds via considerations of what best explains our temporal phenomenology. (shrink)

We argue that generic generalizations about racial groups are pernicious in what they communicate (both to members of that racial group and to members of other racial groups), and may be central to the construction of social categories like racial groups. We then consider how we should change and challenge uses of generic generalizations about racial groups.

In real-time, Twitter strongly imprints world events, popular culture, and the day-to-day; Twitter records an ever growing compendium of language use and change; and Twitter has been shown to enable certain kinds of prediction. Vitally, and absent from many standard corpora such as books and news archives, Twitter also encodes popularity and spreading through retweets. Here, we describe Storywrangler, an ongoing, day-scale curation of over 100 billion tweets containing around 1 trillion 1-grams from 2008 to 2020. For each day, we (...) break tweets into 1-, 2-, and 3-grams across 150+ languages, record usage frequencies, and generate Zipf distributions. We make the data set available through an interactive time series viewer, and as downloadable time series and daily distributions. We showcase a few examples of the many possible avenues of study we aim to enable including how social amplification can be visualized through ‘contagiograms’. (shrink)

Does the Ship of Theseus present a genuine puzzle about persistence due to conflicting intuitions based on “continuity of form” and “continuity of matter” pulling in opposite directions? Philosophers are divided. Some claim that it presents a genuine puzzle but disagree over whether there is a solution. Others claim that there is no puzzle at all since the case has an obvious solution. To assess these proposals, we conducted a cross-cultural study involving nearly 3,000 people across twenty-two countries, speaking eighteen (...) different languages. Our results speak against the proposal that there is no puzzle at all and against the proposal that there is a puzzle but one that has no solution. Our results suggest that there are two criteria—“continuity of form” and “continuity of matter”— that constitute our concept of persistence and these two criteria receive different weightings in settling matters concerning persistence. (shrink)

Teachers in managing their class has always something to recount about their positive and negative experiences that usually occurred in the classroom. These positive and negative experiences affected the holistic disposition of teachers thus, in every small group discussion – both formal and informal, their predicaments regarding their experiences on class management were the primary topic. For the teacher's experiences to be explored and understood this study focused primarily on their experiences in managing class. For this reason, this hermeneutic phenomenological (...) qualitative study focuses on the experiences of the teachers and reflects upon the lived experiences of teachers in class management. This study utilized criterion sampling where ten participants were selected from the teachers of Grade 7 to Grade 10. Data were collected by means of Structured Interviews, and Interpretative Phenomenology Analysis was used to analyze the data. The results of the study show that teachers have been subjected to a number of problems, which result in them losing their patience, especially with students' behavior However, teachers recognized their role in the classroom and provided insightful strategies for combatting the problematic behavior of the students. Considering the management strategy and the personality of the teacher, they were able to realize that even if teaching is a tedious and arduous profession, teachers were still grateful because of the inspiration imparted, happy memories collected, and self-development gained from a fruitful experience in class management. Therefore, teachers whose roles and responsibilities are not limited only to the four walls of the classrooms but it goes beyond their jurisdiction must be given appropriate recognition and compensation. (shrink)

Science communication via testimony requires a certain level of trust. But in the context of ideologically-entangled scientific issues, trust is in short supply—particularly when the issues are politically ‘entangled’. In such cases, cultural values are better predictors than scientific literacy for whether agents trust the publicly-directed claims of the scientific community. In this paper, we argue that a common way of thinking about scientific literacy—as knowledge of particular scientific facts or concepts—ought to give way to a second-order understanding of science (...) as a process as a more important notion for the public’s trust of science. (shrink)

Este ensaio estabelece uma comparação estética e fenomenológica entre os pensamentos de Yves-Klein e Merleau-Ponty. Se o pintor materializou as suas reflexões e concepções em obra pictórica, o fenomenólogo francês dissertou na escrita filosófica o resultado da sua reflexão. Da análise conjunta entre um e outro resulta esta fenomenologia e estética comparativa que apresenta alguns conceitos fundamentais que alimentaram essas reflexões, tais como a visibilidade, o corpo, o mundo. Assim, para além dessa comparação, este ensaio viabiliza o diálogo entre ambos. (...) Palavras-chave: Corpo. Mundo. Visibilidade. Merleau-Ponty. Yves Klein -/- Abstract:This essay establishes an aesthetic and phenomenological comparison between the thoughts of Yves-Klein and Merleau-Ponty. If the painter materialized his reflections and concepts in pictorial work, the French phenomenologist disserted in the philosophical writing the result of his reflection. From the joint analysis between one and the other, this phenomenology and comparative aesthetics results, which presents some fundamental concepts that fed these reflections such as visibility, the body, the world. Thus, in addition to this comparison, this essay enables the dialogue between both. Keywords: Body. World. Visibility. Merleau-Ponty. Yves Klein. (shrink)

In this article, we explore the implications of opposing domains theory for developing ethical leaders. Opposing domains theory highlights a neurological tension between analytic reasoning and socioemotional reasoning. Specifically, when we engage in analytic reasoning, we suppress our ability to engage in socioemotional reasoning and vice versa. In this article, we bring together the domains of neuroscience, psychology, and ethics, to inform our theorizing around ethical leadership. We propose that a key issue for ethical leadership is achieving a healthy balance (...) between analytic reasoning and socioemotional reasoning. We argue that organizational culture often encourages too heavy a reliance on nonemotional forms of reasoning to arrive at moral judgments. As a result, leaders run the risk of suppressing their ability to pay attention to the human side of moral dilemmas and, in doing so, dehumanize colleagues, particularly subordinates, and clients. (shrink)

Epistemic justifications for democracy have been offered in terms of two different aspects of decision-making: voting and deliberation, or ‘votes’ and ‘talk.’ The Condorcet Jury Theorem is appealed to as a justification in terms votes, and the Hong-Page “Diversity Trumps Ability” result is appealed to as a justification in terms of deliberation. Both of these, however, are most plausibly construed as models of direct democracy, with full and direct participation across the population. In this paper, we explore how these results (...) hold up if we vary the model so as to reflect the more familiar democratic structure of a representative hierarchy. We first recount extant analytic work that shows that representation inevitably weakens the voting results of the Condorcet Jury Theorem, but we question the ability of that result to shine light on real representative systems. We then show that, when we move from votes to talk, as modeled in Hong-Page, representation holds its own and even has a slight edge. (shrink)

Ever since Darwin people have worried about the sceptical implications of evolution. If our minds are products of evolution like those of other animals, why suppose that the beliefs they produce are true, rather than merely useful? We consider this problem for beliefs in three different domains: religion, morality, and commonsense and scientific claims about matters of empirical fact. We identify replies to evolutionary scepticism that work in some domains but not in others. One reply is that evolution can be (...) expected to design systems that produce true beliefs in some domain. This reply works for commonsense beliefs and can be extended to scientific beliefs. But it does not work for moral or religious beliefs. An alternative reply which has been used defend moral beliefs is that their truth does not consist in their tracking some external state of affairs. Whether or not it is successful in the case of moral beliefs, this reply is less plausible for religious beliefs. So religious beliefs emerge as particularly vulnerable to evolutionary debunking. (shrink)

As biological and biomedical research increasingly reference the environmental context of the biological entities under study, the need for formalisation and standardisation of environment descriptors is growing. The Environment Ontology (ENVO) is a community-led, open project which seeks to provide an ontology for specifying a wide range of environments relevant to multiple life science disciplines and, through an open participation model, to accommodate the terminological requirements of all those needing to annotate data using ontology classes. This paper summarises ENVO’s motivation, (...) content, structure, adoption, and governance approach. (shrink)

This collection brings together fourteen contributions by authors from around the globe. Each of the contributions engages with questions about how local and global bioethical issues are made to be comparable, in the hope of redressing basic needs and demands for justice. These works demonstrate the significant conceptual contributions that can be made through feminists' attention to debates in a range of interrelated fields, especially as they formulate appropriate responses to developments in medical technology, global economics, population shifts, and poverty.

Ang mga pelikula ng viva max ay namayagpag mula ng magkaroon ng lockdown sa Pilipinas. Sa yugtong ito, nagpalabas ang viva films ng mga pelikula sa pamamagitan ng aplikasyong viva max. Sa panonood ng mga pelikula rito, kailangan mag-subscribe ng manonood. Ang pinakamababng subscription nito ay 149.00. Sa plan na ito, isang buwan ng makakapanood ang subscriber ng lahat ng pelikula ng viva max. Nilalayon ng pananaliksik na ito na talakayin ang kalagayan ng kababaihang gumaganap sa mga piling pelikula ng (...) viva max batay sa kanilang katangian at maging ang papel sa lipunan gamit ang lenteng feminismo. Gumamit ang mananaliksik ng thematic analysis. Sa paggamit ng metodong ito, masusing pinag-aralan at binigyang-kahulugan ang mga impormasyon at datos na susuriin. Naging sandigan din ng pananaliksik na ito ang teoryang feminismo kung saan sinuri ang katangian at papel na ginampanan ng bawat tauhang babae sa mga piling pelikula ng viva max upang mabigyang-linaw ang pagbabagong naganap sa kanilang katauhan. Maging ang dahilan nang patuloy na pagtangkilik ng mga manonood sa ganitong uri ng palabas sa kabila ng iba-ibang palabas na matatagpuan sa ilang aplikasyong katulad ng Netflix, Iflix at Disney. Hindi maikakaila na malaki pa rin ang hatak ng mga pelikula na mapapanood sa viva max. Makikita rin sa pananaliksik na ito ang iba-ibang katangian at kakayahan ng mga kababaihan na tiyak na hahangaan ng sinumang manonood. Mga katangiang hindi binibigyang pansin ng ilang manonood lalo na ng mga kalalakihan ngunit kung susuriin, ito ay nagpapakita ng mahahalagang aral na tiyak na kapupulutan ng aral. Mahalagang talakayin ang ganitong uri ng pananaliksik upang magbigay- linaw kung bakit patuloy itong tinatangkilik sa paglipas ng panahon sa kabila ng paglabas ng mga bagong panoorin. (shrink)

Wittgenstein’s concepts shed light on the phenomenon of schizophrenia in at least three different ways: with a view to empathy, scientific explanation, or philosophical clarification. I consider two different “positive” wittgensteinian accounts―Campbell’s idea that delusions involve a mechanism of which different framework propositions are parts, Sass’ proposal that the schizophrenic patient can be described as a solipsist, and a Rhodes’ and Gipp’s account, where epistemic aspects of schizophrenia are explained as failures in the ordinary background of certainties. I argue that (...) none of them amounts to empathic-phenomenological understanding, but they provide examples of how philosophical concepts can contribute to scientific explanation, and to philosophical clarification respectively. (shrink)

A graph-theoretic account of logics is explored based on the general notion of m-graph (that is, a graph where each edge can have a finite sequence of nodes as source). Signatures, interpretation structures and deduction systems are seen as m-graphs. After defining a category freely generated by a m-graph, formulas and expressions in general can be seen as morphisms. Moreover, derivations involving rule instantiation are also morphisms. Soundness and completeness theorems are proved. As a consequence of the generality of the (...) approach our results apply to very different logics encompassing, among others, substructural logics as well as logics with nondeterministic semantics, and subsume all logics endowed with an algebraic semantics. (shrink)

The Cell Ontology (CL) is designed to provide a standardized representation of cell types for data annotation. Currently, the CL employs multiple is_a relations, defining cell types in terms of histological, functional, and lineage properties, and the majority of definitions are written with sufficient generality to hold across multiple species. This approach limits the CL’s utility for cross-species data integration. To address this problem, we developed a method for the ontological representation of cells and applied this method to develop a (...) dendritic cell ontology (DC-CL). DC-CL subtypes are delineated on the basis of surface protein expression, systematically including both species-general and species-specific types and optimizing DC-CL for the analysis of flow cytometry data. This approach brings benefits in the form of increased accuracy, support for reasoning, and interoperability with other ontology resources. 104. Barry Smith, “Toward a Realistic Science of Environments”, Ecological Psychology, 2009, 21 (2), April-June, 121-130. Abstract: The perceptual psychologist J. J. Gibson embraces a radically externalistic view of mind and action. We have, for Gibson, not a Cartesian mind or soul, with its interior theater of contents and the consequent problem of explaining how this mind or soul and its psychological environment can succeed in grasping physical objects external to itself. Rather, we have a perceiving, acting organism, whose perceptions and actions are always already tuned to the parts and moments, the things and surfaces, of its external environment. We describe how on this basis Gibson sought to develop a realist science of environments which will be ‘consistent with physics, mechanics, optics, acoustics, and chemistry’. (shrink)

This paper argues that the activist, feminist and pragmatist Jane Addams was an experimental philosopher. To defend this claim, I argue for capacious notions of both philosophical pragmatism and experimental philosophy. I begin in Section 2 with a new defence of Rose and Danks’ [‘In Defense of a Broad Conception of Experimental Philosophy’. Metaphilosophy 44, no. 4 : 512–32] argument in favour of a broad conception of experimental philosophy. Koopman [‘Pragmatist Resources for Experimental Philosophy: Inquiry in Place of Intuition’. (...) Journal of Speculative Philosophy 26, no. 1 : 1–24] argues that many twentieth-century American pragmatists can make important contributions to contemporary experimental philosophy. In Section 3, I argue that while this may be true, it is also true that under the broad conception, many of the pragmatists just were experimental philosophers. In Section 4, I argue that as a pragmatist philosopher in her own right, Jane... (shrink)

Aims: The Research Diagnostic Criteria for Temporomandi¬bular Disorders (RDC/TMD) Axis I diagnostic algorithms were demonstrated to be reliable but below target sensitivity and specificity. Empirical data supported Axis I algorithm revisions that were valid. Axis II instruments were shown to be both reliable and valid. An international consensus workshop was convened to obtain recommendations and finalization of new Axis I diagnostic algorithms and new Axis II instruments. Methods: A comprehensive search of published TMD diagnostic literature was followed by review and (...) consensus via a formal structured process by a panel of experts for revision of the RDC/TMD. Results: The recommended Diagnostic Criteria for TMD (DC/TMD) Axis I protocol includes both a valid screener for pain diagnoses and valid criteria for the most common pain-related TMDs and for one intra-articular disorder. The Axis II protocol retains selected RDC/TMD screening instruments augmented with new instruments to better assess the interactions between pain and psychosocial functioning. A comprehensive classification system is also presented. Conclusion: The recommended evidence-based DC/TMD protocol is appropriate for use in both the clinical and research settings. Simple Axis I and II screening tests augmented by validated Axis I and Axis II instruments allow for identification of simple to complex TMD patients. (shrink)

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

This essay proposes that Socrates practiced various spiritual exercises, including meditation, and that this Socratic practice of meditation was habitual, aimed at cultivating emotional self-control and existential preparedness. Contemporary research in neurobiology supports the view that intentional mental actions, including meditation, have a profound impact on brain activity, neuroplasticity, and help engender emotional self-control. This impact on brain activity is confirmed via technological developments, a prime example of how technology benefits humanity. Socrates attains the balanced emotional self-control that Alcibiades describes (...) in the Symposium because of the sustained mental effort he exerts that directly impacts his brain and his emotional and philosophical life. The essay concludes that Socratic meditative practices aimed at manifesting true dignity as human beings within the complexities of a technological world offer a promising model of self-care worthy of embracing today. (shrink)

Because corporate social responsibility can be beneficial to both companies and its stakeholders, interest in factors that support CSR performance has grown in recent years. A thorough integration of CSR in core business processes is particularly important for achieving effective long-term CSR practices. Here, we explored the individual CSR-related competencies that support CSR implementation in a corporate context. First, a systematic literature review was performed in which relevant scientific articles were identified and analyzed. Next, 28 CSR directors and managers were (...) interviewed. The literature review complemented with interview data resulted in the following eight distinct CSR-related competencies: Anticipating CSR challenges; Understanding CSR-relevant systems and subsystems; Understanding CSR-relevant standards; CSR management competencies, including Leading CSR programs, Managing CSR programs, and Identifying and realizing CSR-related business opportunities; Realizing CSR-supportive interpersonal processes; Employing CSR-supportive personal characteristics and attitudes; Personal value-driven competencies, including Ethical normative competencies, Balancing personal ethical values and business objectives, and Realizing self-regulated CSR-related behaviors and active involvement; and Reflecting on personal CSR views and experiences. Based on these results, implications for further research on this topic, as well as implications for practitioners, are discussed. (shrink)

Providing heroin to heroin addicts taking part in medical trials to assess the effectiveness of the drug as a treatment alternative, breaches ethical research standards, some ethicists maintain. Heroin addicts, they say, are unable to consent voluntarily to take part in these trials. Other ethicists disagree. In our view, both sides of the debate have an inadequate understanding of voluntariness. In this article we therefore offer a fuller conception, one which allows for a more flexible, case-to-case approach in which some (...) heroin addicts are considered capable of consenting voluntarily, others not. An advantage of this approach, it is argued, is that it provides a safety net to minimize the risk of inflicting harm on trial participants. (shrink)